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Role Of Dna Damage And Repair In Cell Aging

RRP $34.99

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Aging occurs at the level of individual cells, a complex interplay between intrinsic "programming" and exogenous "wear and tear," with genetically-determined cellular capacity to repair environmentally-induced DNA damage playing a central role in the rate of aging and its specific manifestations. In 12 chapters, "The Role of DNA Damage and Repair in Cell Aging" provides an intellectual framework for aging of mitotic and post-mitotic cells, describes a variety of model systems for further studies, and reviews current concepts of DNA responses and their relationship to the phenomenon of aging.


As part of a series entitled "Advances in Cell Aging and Gerontology," this volume also summarizes seminal recent discoveries such as the molecular basis for Werner syndrome (a mutant DNA helicase), the complementary roles of telomere shortening and telomerase activity in cell senescence versus immortalization, the role of apoptosis in the homeostasis of aging tissue, and the existence of an inducible SOS-like response in mammalian cells that minimizes DNA damage from repeatedly encountered injurious environmental agents. Insights into the relationship between cellular aging and age-associated diseases, particularly malignancies, are also provided in several chapters.


This book is an excellent single source of information for anyone interested in DNA repair, mechanisms of aging, or certainly their intersection. Students will gain a general appreciation of these fields, but even the most senior investigators will benefit from the detailed coverage of rapidly advancing areas.


A Family Affair

RRP $241.99

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The family unit has been a central theme in movies since the earliest days of the medium- whether as a locus of domestic bliss, a dysfunctional source of drama, a collection of comic personalities or an inferno of repressed feelings. This new anthology brings the subject into sharp focus, collecting a range of multidisciplinary perspectives that attempt to directly penetrate the questions raised by the role of the family onscreen. Discussing a wide range of contemporary and classic films, fromHouse of Strangers (1949) and Mary Poppins (1964) to Superstar (1987),The Royal Tenenbaums (2001) and Brokeback Mountain (2005), this study addresses the nature of family values in cinema, and the 'family' nature of the Hollywood production system itself. With a wealth of historical background and contemporary analysis, this volume is a penetrating view of the oldest and most influential social institution as imagined for the screen.


A Day In The Life Of A Student Affairs Educator

RRP $337.99

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This book constitutes a collection of case studies that explore issues faced by new professionals in student affairs, with the scenarios designed to develop ACPA/NASPA Professional Competencies.

These cases provide opportunities to create meaningful learning experiences for courses, training programs, and the mentoring new professionals, giving them exposure to the kinds of dilemmas they will encounter as they assume their leadership roles or start out on supervisory positions.

The cases are derived from interviews with current student affairs professionals, are based on real life dilemmas, reflect contemporary issues on our college campuses, and are designed to be easily used or adapted across all institutional types.

The cases cover the areas of advising and helping; assessment, evaluation and research; equity, diversity and inclusion; ethical professional practice; history, values and philosophy; human and organizational resources; law, policy and governance; leadership; personal foundations; and student learning and development, and vary in length to allow for multiple uses. Shorter cases can be role played and discussed in leadership training workshops, while longer cases can be used as take-home assignments or debated during longer training sessions.

The book begins with advice on how to use the cases, and concludes with general advice provided by current professionals in the field.

The Authors
Anne Hornak is currently Associate Professor of Educational Leadership at Central Michigan University where she teaches courses related to ethical leadership, college student development, and higher education administration. Dr. Hornak conducts research on White identity development, financial challenges of today's students, and intercultural competence.

Sarah Marshall is currently Associate Professor of Educational Leadership and Director of the Doctor of Education Program at Central Michigan University (CMU) where she teaches courses related to today's college student, student affairs administration, student development, and higher education administration


Rise And Decline Of Industry In Central And Eastern Europe

RRP $75.00

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In the course of the tremendous political and economic upheaval starting in 1989/1990 many industrial cities and regions in Central and Eastern Europe have been confronted with profound problems. This book presents eleven detailed national reports which describe the situation in such cities and regions as well as the strategies which have been employed to cope with structural change. The country reports are complemented by short case studies of selected cities and regions. An introduction gives background to such topics as structural change and the ramifications of EU enlargement. Finally some conclusions are drawn and recommendations offered for future policy.


The Airline Profit Cycle

RRP $300.99



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